Clinical Research Directory

Inclusion Criteria: * Chronic renal failure patient at stage 4 or 5 (i.e. estimated GFR \< 30mL/min/1.73m2); or Dialysis patient; or renal transplant patient regardless of GFR; * Age ≥ 18 years; * Indication for influenza vaccination; * Express free and informed consent. Exclusion Criteria: * Known hypersensitivity to influenza vaccine or egg proteins; * Previous influenza vaccination for the current season; * Current infection; * Current acute illness; * Treatments with a major impact on vaccine response: * Treatment of rejection within the previous 3 months; * Renal transplantation with induction performed within the previous 6 months; * Immunosuppressive treatment including CTLA4 agonist, complement inhibitor, anti-CD20; * Treatments that may distort the serological response: Polyvalent immunoglobulin infusion within the preceding 3 months; * Vulnerable persons (minors, adults under guardianship or trusteeship, persons deprived of their liberty, persons unable to speak French); * Subjects not affiliated to Social Security.