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NCT06907693

The Effects of Drug Candidate CS1 on Lung Structure and Function Utilizing FRI

Sponsor: Prisma Health-Upstate

View on ClinicalTrials.gov

Summary

Explore the impact of drug candidate CS1 on pathological vascular remodeling of small pulmonary arteries in the disease pulmonary arterial hypertension (PAH). This sub-study for CS1-004 aims to utilize FRI, an innovative, non-invasive imaging technology to visualize how long-term use of CS1 influences structural changes in pulmonary arteries. This sub-study seeks to provide valuable insights into the potential of CS1 to transform PAH treatment in some patients enrolled in the Expanded Access Program (CS1-004).

Official title: The Effects of Drug Candidate CS1 on Lung Structure and Function Utilizing FRI, a Non-Invasive, Functional Respiratory Imaging System

Key Details

Gender

All

Age Range

Any - Any

Study Type

OBSERVATIONAL

Enrollment

7

Start Date

2025-03-14

Completion Date

2026-03-15

Last Updated

2026-02-06

Healthy Volunteers

No

Interventions

DIAGNOSTIC_TEST

CT Pulmonary Angiography Scan

Computed tomography (CT) pulmonary angiography scan of the chest with IV contrast

Locations (1)

Prisma Health

Greenville, South Carolina, United States