Clinical Research Directory
Browse clinical research sites, groups, and studies.
Clinical Study of 18F-Labeled FAPI-04 in PET Imaging of Breast Cancer
Sponsor: The Affiliated Hospital of Qingdao University
Summary
This study aims to evaluate the diagnostic accuracy (sensitivity, specificity, positive/negative predictive value, and overall accuracy) of 18F-FAPI-04 PET imaging in breast cancer for detecting fibroblast activation protein (FAP)-rich lesions. Additionally, the study will longitudinally monitor dynamic changes in FAP expression levels and tumor size during therapy, including chemotherapy, targeted therapy, or immunotherapy.The non-invasive nature of 18F-FAPI-04 PET addresses limitations of traditional biopsy-dependent stromal evaluation, offering whole-body quantification of tumor microenvironment dynamics to optimize therapeutic decision-making.
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
OBSERVATIONAL
Enrollment
30
Start Date
2025-04-11
Completion Date
2027-12
Last Updated
2025-04-29
Healthy Volunteers
No
Conditions
Interventions
18F-FAPI-04 PET scan
FAPI-04, labeled with PET radio-nuclide 18F will be used as a molecular imaging tracer for PET scan. All participants will undergo 18F-FAPI-04 PET scan.
Locations (1)
The Affiliated Hospital of Qingdao University
Qingdao, Shandong, China