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Clinical Trial Evaluating Safety and Efficacy of Resomelagon on Dengue Infection (RESOVIR-2)
Sponsor: Federal University of Minas Gerais
Summary
The goal of this clinical trial is to understand if Resomelagon can treat adult patients with Dengue virus infection. The main questions the investigators aim to answer are: Is Resomelagon safe to use in patients with Dengue? Is Resomelagon able to reduce the duration of illness? (defined by clinical and laboratory criteria) Participants will be allocated to Resomelagon or placebo groups in this study and asked to take the medication and submitted to blood tests.
Official title: A Randomized, Double-blind, Placebo-controled, Phase 2a Trial Evaluating the Safety and Initial Efficacy of Resomelagon in Patients With Dengue Infection
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
120
Start Date
2026-02
Completion Date
2027-12
Last Updated
2025-08-28
Healthy Volunteers
No
Conditions
Interventions
Resomelagon
Resomelagon 100mg, orally, once daily.
Placebo
Placebo
Standard Treatment
Hydration and symptomatic therapy as indicated for Dengue fever.
Locations (2)
Clinical Research Unit
Belo Horizonte, Minas Gerais, Brazil
Centro Integrado de Pesquisa
São José do Rio Preto, São Paulo, Brazil