Clinical Research Directory

Inclusion Criteria: * Patients with no treatment or on constant medicinal therapy, expected to remain constant: mesalamine for at least 6 weeks, steroids at least 2 weeks (≤20mg prednisone or budesonide ≤6mg), immunomodulatory at least 12 weeks or biologics/ small molecules for at least 12 weeks therapy. Patients who initiate the study on steroids will remain on a constant dose throughout the study. * If patients stopped therapy prior to the study then they should be at least 2 weeks from stopping steroids or 5ASA, or 4 weeks from stopping small molecules, 8 weeks from stopping biologics, or 12 weeks from stopping thiopurines. * CD patients will be included if their symptoms score \>4 and ≤15 on the HBI score * Fecal calprotectin\>150ug/gr or evidence of an active disease per IUS defined as increased blood flow (modified Limberg score\>0) or thickness of bowel wall\>3mm Exclusion Criteria: * Inability to commit for performing at least 10-15 minutes of exercise, 6 times a week. * Lack of availability or capability to use a computer/ internet. * Any proven current infection such as, fever, active abscess, Clostridioides difficile infection, positive stool culture, or parasite in patients with chronic diarrhea. * Inability to sign informed consent and/ or complete the study protocol. * Incompetent individuals who are unable to provide informed consent. * Planed pregnancy or pregnancy- up to 3 months post labor. * Subjects with chronic conditions such as active arthritis, cancer (within the previous 5 years, not including BCC, SCC), organ transplant subjects, advanced kidney or liver disease, or systemic inflammatory conditions other than IBD. * Patients who underwent surgery in the previous 3 months, had more than 1 surgery of intestinal resection, patients with ileostomy, pouch or patients with short bowel (small intestine\<1.5 meter). * Patients with a significant abdominal wall hernia, unless received a written confirmation from a treating surgeon. * Active peri-anal disease (fistula, abscess, fissure), stricturing or penetrating disease * Active extra-intestinal manifestations (not excluded are- oral aphthae and peripheral arthralgia without arthritis) * Patients on total parenteral nutrition (TPN) or on exclusive enteral nutrition (EEN). * Probiotics or antibiotics in the 15 days prior to enrollment or during the study period.