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Evaluation of Analgesic Efficacy of Lidocaine and Diclofenac Spray in Radial Artery Blood Gas Sampling by Visual Analogue Scale and Perfusion Index
Sponsor: Haydarpasa Numune Training and Research Hospital
Summary
The aim of this clinical trial is to evaluate the analgesic efficacy of lidocaine and diclofenac sprays to be administered before the procedure in cases admitted to the emergency department and requiring radial artery blood gas sampling by means of visual pain scale (VAS) and perfusion index in comparison with placebo. The main questions it aims to answer are: 1\. Is there a difference between the efficacy of two different sprays? 2. Is there a significant difference between the side effects of two different sprays? Researchers will compare diclofenac sodium, lidocain and placebo sprays. Treatments will; 1. be administered in same three spray bottles to ensure blinding in the groups. 2. Randomisation will be done by closed envelope method. 3. Numerical Pain Scale (NRS) will be used to evaluate the analgesic efficacy of the sprays. NRS scores will be recorded in both groups before starting blood gas sampling (baseline) and after blood gas sampling. 4. Any side effects due to medication will be recorded.
Official title: Evaluation of Analgesic Efficacy of Lidocaine and Diclofenac Spray in Radial Artery Blood Gas Sampling by Visual Analogue Scale (VAS) and Perfusion Index: A Randomised, Placebo-Controlled Study
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
150
Start Date
2024-11-01
Completion Date
2025-06-30
Last Updated
2025-06-26
Healthy Volunteers
No
Conditions
Interventions
Diclofenac
Group II: 5-6 puffs of topical 1% diclofenac spray will be applied before radial artery blood gas sampling.
Lidocaine spray
Group I: 5-6 puffs of topical 10% lidocaine spray will be applied before radial artery blood gas sampling.
Placebo
Group III: 5-6 puffs of topical 70% alcohol solution spray will be applied before radial artery blood gas sampling.
Locations (1)
Haydarpasa Numune Training and Research Hospital
Istanbul, Uskudar, Turkey (Türkiye)