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ACTIVE NOT RECRUITING
NCT06918340
PHASE4

Evaluation of Analgesic Efficacy of Lidocaine and Diclofenac Spray in Radial Artery Blood Gas Sampling by Visual Analogue Scale and Perfusion Index

Sponsor: Haydarpasa Numune Training and Research Hospital

View on ClinicalTrials.gov

Summary

The aim of this clinical trial is to evaluate the analgesic efficacy of lidocaine and diclofenac sprays to be administered before the procedure in cases admitted to the emergency department and requiring radial artery blood gas sampling by means of visual pain scale (VAS) and perfusion index in comparison with placebo. The main questions it aims to answer are: 1\. Is there a difference between the efficacy of two different sprays? 2. Is there a significant difference between the side effects of two different sprays? Researchers will compare diclofenac sodium, lidocain and placebo sprays. Treatments will; 1. be administered in same three spray bottles to ensure blinding in the groups. 2. Randomisation will be done by closed envelope method. 3. Numerical Pain Scale (NRS) will be used to evaluate the analgesic efficacy of the sprays. NRS scores will be recorded in both groups before starting blood gas sampling (baseline) and after blood gas sampling. 4. Any side effects due to medication will be recorded.

Official title: Evaluation of Analgesic Efficacy of Lidocaine and Diclofenac Spray in Radial Artery Blood Gas Sampling by Visual Analogue Scale (VAS) and Perfusion Index: A Randomised, Placebo-Controlled Study

Key Details

Gender

All

Age Range

18 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

150

Start Date

2024-11-01

Completion Date

2025-06-30

Last Updated

2025-06-26

Healthy Volunteers

No

Interventions

DRUG

Diclofenac

Group II: 5-6 puffs of topical 1% diclofenac spray will be applied before radial artery blood gas sampling.

DRUG

Lidocaine spray

Group I: 5-6 puffs of topical 10% lidocaine spray will be applied before radial artery blood gas sampling.

OTHER

Placebo

Group III: 5-6 puffs of topical 70% alcohol solution spray will be applied before radial artery blood gas sampling.

Locations (1)

Haydarpasa Numune Training and Research Hospital

Istanbul, Uskudar, Turkey (Türkiye)