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RECRUITING
NCT06920641
NA

Effects of Tagatose on Glycemic Response and Gastrointestinal Microbiota in Healthy Adults

Sponsor: PepsiCo Global R&D

View on ClinicalTrials.gov

Summary

The primary objective of this clinical-trial is to determine, in subjects with impaired fasting glucose (IFG) and/or insulin resistance (IR), if tagatose meets the definition of a prebiotic, namely that consuming tagatose for 4 weeks selectively stimulates the selective growth of bacteria in the colon and is associated with a health benefit (oral glucose tolerance) when compared to consuming the control treatment (10g sucrose) for 4 weeks.

Official title: Effects of Tagatose on Glycemic Response and Gastrointestinal Microbiota: A Randomized, Placebo-Controlled, Double-Blind, Crossover Trial in Healthy Adults

Key Details

Gender

All

Age Range

18 Years - 50 Years

Study Type

INTERVENTIONAL

Enrollment

55

Start Date

2025-03-25

Completion Date

2025-12-31

Last Updated

2025-04-10

Healthy Volunteers

Yes

Interventions

OTHER

Tagatose

Sachet containing 10g tagatose to be dissolved in 250ml water and taken once daily on Days 1-28 of a 4-week dosing period. (1 of 2 dosing periods separated by a 4-week washout)

OTHER

Placebo

Sachet containing 10g sucrose to be dissolved in 250ml water and taken once daily on Days 1-28 of a 4-week dosing period. (1 of 2 dosing periods separated by a 4-week washout)

Locations (1)

INQUIS Clinical Research

Toronto, Ontario, Canada