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NOT YET RECRUITING
NCT06921525
PHASE1/PHASE2

Comparing Efficacy of Tea Tree Oil Versus Topical Azithromycin in Treating Dry Eye

Sponsor: Ehab Mohamed Elsayed Mohamed Saad

View on ClinicalTrials.gov

Summary

This study aims to compare the effects of azithromycin and tea tree oil on the clinical outcomes and inflammatory profile of patients with MGD-associated DED. By focusing on changes in tear IL-8 and IL-17 levels, the study seeks to provide insights into the differential mechanisms of these two treatments and their potential in addressing inflammation-driven DED.

Official title: Comparing Efficacy of Tea Tree Oil Versus Topical Azithromycin in Treating Dry Eye Disease Associated With Meibomian Gland Dysfunction: A Focus on Tear Interleukin Level

Key Details

Gender

All

Age Range

18 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

44

Start Date

2025-04-01

Completion Date

2025-08-01

Last Updated

2025-04-10

Healthy Volunteers

No

Conditions

Interventions

DRUG

Tea Tree Oil Topical Application Oil

Tea tree oil (TTO), derived from the leaves of Melaleuca alternifolia,

DRUG

Azithromycin Ophthalmic Solution

Azithromycin has demonstrated efficacy in improving meibomian gland function and reducing inflammation and improving symptoms of dryness of the eye