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Changes in the Urinary Microbiome and Metabolome During Treatment of the Overactive Bladder in Female Patients
Sponsor: University Hospital Ostrava
Summary
This is a non-interventional study that will not pose any burden for the participants. The study subjects will be examined and treated in a standard manner according to current clinical recommendations for the treatment of overactive bladder (OAB). A portion of urine samples, which are routinely collected for biochemical and culture examinations as part of the diagnostic process, will be sent for examination of the characteristics of the urinary microbiome and metabolome (UMM) before and after treatment.
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
80
Start Date
2025-05-01
Completion Date
2027-12-31
Last Updated
2025-05-04
Healthy Volunteers
No
Conditions
Interventions
Urine Microbiological and Metabolomic Analysis
Microbiological and metabolomic analysis of a urine sample will be performed in the study subjects, before and after the end of the treatment.
Locations (4)
University Hospital Ostrava
Ostrava, Moravian-Silesian Region, Czechia
Thomayer University Hospital
Prague, Czechia
Institute of Microbiology of the Czech Academy of Sciences
Prague, Czechia
University Hospital Bulovka
Prague, Czechia