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The Effect of Exercise on Metabolic Alteration
Sponsor: Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences
Summary
The goal of this clinical trial is to study the effectiveness of aerobic exercise in treating obesity in adults and to assess the efficacy of exercise. The primary research questions it seeks to address are as follows: * To what extent does exercise increase the total energy expenditure of participants? * Why and how does the energy expenditure from exercise not fully compensate for the total energy expenditure (TEE)? * Researchers will assess the efficacy and potential challenges of using exercise as a treatment for obesity by comparing the measurement data before exercise intervention (week 0), immediately after exercise intervention (week 12), and 8 weeks post-completion of exercise intervention (week 20). Participants will engage in the following activities: * Engage in running sessions supervised five times a week for a duration of 12 weeks. * Attend laboratory sessions both before and after the exercise intervention period for metabolic and anthropometric measurements, as well as sample collection. * Return to the laboratory for further metabolic and anthropometric measurements and sample collection8 weeks post-completion of exercise intervention.
Official title: Metabolic Response of Sedentary Participants to a Long-term Exercise Intervention
Key Details
Gender
All
Age Range
18 Years - 40 Years
Study Type
INTERVENTIONAL
Enrollment
80
Start Date
2025-05-01
Completion Date
2027-12
Last Updated
2026-01-21
Healthy Volunteers
Yes
Interventions
Exercise intervention
Exercise prescription for participant, * 150Kcal for Weeks 1-4 (gradually increase to 150Kcal in the first two weeks as familiar stage), * 250Kcal for Weeks 5-8, * 350Kcal for Weeks 9-12.
Locations (1)
Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences
Shenzhen, Guangdong, China