Clinical Research Directory
Browse clinical research sites, groups, and studies.
Evaluating the Preliminary Efficacy and Safety of JS207 in NSCLC After Progression Following Platinum-based Chemotherapy and Immunotherapy
Sponsor: Shanghai Junshi Bioscience Co., Ltd.
Summary
This is a multiple-arm, open phase II clinical trial evaluating the safety, tolerability,and preliminary efficacy of JS207 in NSCLC after progression following Platinum-based chemotherapy and immunotherapy.
Official title: A Phase II Study of JS207 (PD-1/VEGF Dual Antibody) in Combination With or Without JS004 or Docetaxel in Advanced Non-small Cell Lung Cancer With Disease Progression During or After the Treatment of Platinum-based Chemotherapy and Immunotherapy
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
66
Start Date
2025-07-15
Completion Date
2026-06-26
Last Updated
2026-02-06
Healthy Volunteers
No
Conditions
Interventions
JS207 injection +docetaxel
Patients receive JS207 10mg/kg or other dosage and docetaxel 75mg/m2, q3w.
JS207 injection +JS004 injection
Patients receive JS207 10mg/kg or other dosage and JS004 200mg, q3w.
JS207 injection
Patients receive JS207 10mg/kg or other dosage.
Locations (18)
Beijing Chest Hospital, Capital Medical University
Beijing, Beijing Municipality, China
Jilin Cancer Hospital
Jilin, Changchun, China
Hunan Cancer Hospital
Hunan, Changsha, China
West China Hospital, Sichuan University
Sichuan, Chengdu, China
Second Affiliated Hospital, PLA Academy of Military Medical Sciences
Chongqing, Chongqing Municipality, China
Army Medical Center, PLA
Chongqing, Chongqing Municipality, China
The First Affiliated Hospital of Guangzhou Medical University
Guangdong, Guangzhou, China
Harbin Medical University Cancer Hospital
Heilongjiang, Harbin, China
Anyang Tumor Hospital
Anyang, Henan, China
The First Affiliated Hospital of Henan University of Science and Technology
Luoyang, Henan, China
The First Affiliated Hospital of Xinxiang Medical University
Xinxiang, Henan, China
The First People's Hospital of Changde
Changde, Hunan, China
The First Affiliated Hospital of Nanchang University
Jiangxi, Nanchang, China
Shanghai Pulmonary Hospital
Shanghai, Shanghai Municipality, China
The Third People's Hospital of Datong
Datong, Shanxi, China
Yibin Second People's Hospital
Yibin, Sichuan, China
Affiliated Tumor Hospital of Xinjiang Medical University
Xinjiang, Xinjiang, China
Shanghai Pulmonary Hospital
Shanghai, China