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RECRUITING
NCT06925152
PHASE4

COMFORT Trial: Complex Obstetric Management With Focused Regional Transversus Abdominis Plane Block

Sponsor: University of Tennessee

View on ClinicalTrials.gov

Summary

To assess the effect of intraoperative transversus abdominis plane (TAP) blocks on the amount of opioid pain medications expressed as morphine milliequivalents (MME) used postoperatively in patients who have undergone cesarean delivery (CD) in the setting of complex obstetric surgery (COS).

Key Details

Gender

FEMALE

Age Range

18 Years - 50 Years

Study Type

INTERVENTIONAL

Enrollment

120

Start Date

2025-07-15

Completion Date

2028-05

Last Updated

2026-03-11

Healthy Volunteers

No

Interventions

DRUG

Bupivicaine intervention arm

TAP blocks in intervention group will include 0.5% bupivacaine in 30mL solution of 15mL normal saline and 15mL bupivacaine

DRUG

Placebo arm

Placebo group TAP block syringe will include 30mL normal saline

Locations (1)

Regional One Health

Memphis, Tennessee, United States