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COMFORT Trial: Complex Obstetric Management With Focused Regional Transversus Abdominis Plane Block
Sponsor: University of Tennessee
Summary
To assess the effect of intraoperative transversus abdominis plane (TAP) blocks on the amount of opioid pain medications expressed as morphine milliequivalents (MME) used postoperatively in patients who have undergone cesarean delivery (CD) in the setting of complex obstetric surgery (COS).
Key Details
Gender
FEMALE
Age Range
18 Years - 50 Years
Study Type
INTERVENTIONAL
Enrollment
120
Start Date
2025-07-15
Completion Date
2028-05
Last Updated
2026-03-11
Healthy Volunteers
No
Conditions
Interventions
Bupivicaine intervention arm
TAP blocks in intervention group will include 0.5% bupivacaine in 30mL solution of 15mL normal saline and 15mL bupivacaine
Placebo arm
Placebo group TAP block syringe will include 30mL normal saline
Locations (1)
Regional One Health
Memphis, Tennessee, United States