Clinical Research Directory

Inclusion Criteria: Intervention group * RYGB-operated ≥ 18 months prior to inclusion * History of diabetes prior to RYGB (HbA1c ≥48 mmol/mol or use of antidiabetic medication) * HbA1c \<58 mmol/mol on no antidiabetic medication or metformin alone * Weight change \< ±3 kg for \>3 months at time of inclusion Control group A * No history of diabetes * HbA1c \<48 mmol/mol at time of inclusion * Fasting plasma glucose \< 7.0 mmol/L at time of inclusion * Weight change \< ±3 kg for \>3 months at time of inclusion Control group B * Type 2 diabetes (HbA1c ≥48 mmol/mol or use of antidiabetic medication at time of inclusion) * Weight change \< ±3 kg for \>3 months at time of inclusion Exclusion Criteria: * Pregnancy or breastfeeding * Haemoglobin \< 6.5 mmol/L at time of inclusion * Fasting plasma glucose \> 10.0 mmol/L at time of inclusion * Prior cholecystectomy * Chronic or tendency to diarrhoea