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Cell-free DNA in Acute Stroke
Sponsor: University Hospital, Basel, Switzerland
Summary
Cell-free DNA (cfDNA) is an important pro-inflammatory and prothrombotic mediator. With this study the investigators aim to gain new insights into the role of cfDNA in stroke and to perform a combined analysis of cfDNA in the hyperacute phase of the disease using blood and thrombus analyses. The main objectives are to analyse cfDNA in different stroke etiologies, to investigate the relationship between cfDNA and important procedural factors such as secondary embolisation and reperfusion outcomes, to analyse the correlation between blood and thrombus content of cfDNA and to investigate the specific source of cfDNA in distinct stroke subtypes.
Official title: CANTO - Cell-free DNA in Acute Stroke
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
200
Start Date
2025-03-30
Completion Date
2026-09-01
Last Updated
2025-04-15
Healthy Volunteers
No
Conditions
Locations (1)
University Hospital Basel
Basel, Switzerland