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Real-world Effectiveness, Safety and Immunogenicity of Chikungunya Vaccination in Populations at Risk of Severe or Complicated Forms: Prospective Study in La Réunion
Sponsor: Centre Hospitalier Universitaire de la Réunion
Summary
Against the backdrop of a growing chikungunya epidemic in La Réunion, this prospective study will assess the real-life efficacy, safety and immunogenicity of IXCHIQ® vaccine in vulnerable individuals (seniors, comorbid patients), defined by the French Health Autority (HAS) as at risk of severe or complicated forms and/or chronic disabling forms (chronic arthritis, chronic fatigue phenotypes). This study will also provide input for the preparation of a cluster randomized trial on a population scale.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
1800
Start Date
2025-04-18
Completion Date
2026-10
Last Updated
2025-07-29
Healthy Volunteers
No
Conditions
Interventions
IXCHIQ
Group of vaccinated arm will be with the IXCHIQ vaccine
Locations (1)
CHU La Réunion
Saint-Denis, France