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RECRUITING
NCT06928753
PHASE4

Real-world Effectiveness, Safety and Immunogenicity of Chikungunya Vaccination in Populations at Risk of Severe or Complicated Forms: Prospective Study in La Réunion

Sponsor: Centre Hospitalier Universitaire de la Réunion

View on ClinicalTrials.gov

Summary

Against the backdrop of a growing chikungunya epidemic in La Réunion, this prospective study will assess the real-life efficacy, safety and immunogenicity of IXCHIQ® vaccine in vulnerable individuals (seniors, comorbid patients), defined by the French Health Autority (HAS) as at risk of severe or complicated forms and/or chronic disabling forms (chronic arthritis, chronic fatigue phenotypes). This study will also provide input for the preparation of a cluster randomized trial on a population scale.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

1800

Start Date

2025-04-18

Completion Date

2026-10

Last Updated

2025-07-29

Healthy Volunteers

No

Interventions

BIOLOGICAL

IXCHIQ

Group of vaccinated arm will be with the IXCHIQ vaccine

Locations (1)

CHU La Réunion

Saint-Denis, France