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RECRUITING
NCT06929624
PHASE3

A Phase 3 Clinical Study of SHR-A1912 Combined With R-GemOx Versus R-GemOx in Diffuse Large B-cell Lymphoma

Sponsor: Suzhou Suncadia Biopharmaceuticals Co., Ltd.

View on ClinicalTrials.gov

Summary

This is a multicenter, randomized, open-label, phase 3 clinical study to evaluate the efficacy of SHR-A1912 combined with R-GemOx in relapsed refractory diffuse large B-cell lymphoma.

Official title: A Phase 3, Open-label, Randomized Study of SHR-A1912 Combined With Rituximab + Gemcitabine + Oxaliplatin (R-GEMOX) Versus R-GEMOX in Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma

Key Details

Gender

All

Age Range

18 Years - 80 Years

Study Type

INTERVENTIONAL

Enrollment

280

Start Date

2025-04-24

Completion Date

2028-01

Last Updated

2025-11-18

Healthy Volunteers

No

Interventions

DRUG

SHR-A1912 Injection

SHR-A1912 injection.

DRUG

Rituximab Injection

Rituximab injection.

DRUG

Gemcitabine Hydrochloride for Injection

Gemcitabine hydrochloride for injection.

DRUG

Oxaliplatin Injection

Oxaliplatin injection.

Locations (2)

Beijing Cancer Hospital

Beijing, Beijing Municipality, China

Sun Yat-sen University Cancer Center

Guangzhou, Guangdong, China