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A Phase 3 Clinical Study of SHR-A1912 Combined With R-GemOx Versus R-GemOx in Diffuse Large B-cell Lymphoma
Sponsor: Suzhou Suncadia Biopharmaceuticals Co., Ltd.
Summary
This is a multicenter, randomized, open-label, phase 3 clinical study to evaluate the efficacy of SHR-A1912 combined with R-GemOx in relapsed refractory diffuse large B-cell lymphoma.
Official title: A Phase 3, Open-label, Randomized Study of SHR-A1912 Combined With Rituximab + Gemcitabine + Oxaliplatin (R-GEMOX) Versus R-GEMOX in Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
280
Start Date
2025-04-24
Completion Date
2028-01
Last Updated
2025-11-18
Healthy Volunteers
No
Conditions
Interventions
SHR-A1912 Injection
SHR-A1912 injection.
Rituximab Injection
Rituximab injection.
Gemcitabine Hydrochloride for Injection
Gemcitabine hydrochloride for injection.
Oxaliplatin Injection
Oxaliplatin injection.
Locations (2)
Beijing Cancer Hospital
Beijing, Beijing Municipality, China
Sun Yat-sen University Cancer Center
Guangzhou, Guangdong, China