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Effectiveness of Midodrine as an Adjuvant to Norepinephrine in Weaning Critically Ill Patients From Vasopressors
Sponsor: Sohag University
Summary
This study aims to evaluate the effectiveness of midodrine as an adjuvant to norepinephrine in weaning critically ill patients from vasopressors
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
112
Start Date
2025-03-13
Completion Date
2025-10-13
Last Updated
2025-04-16
Healthy Volunteers
No
Conditions
Interventions
Weaning critically ill patients from norepinephrine using midodrine as an adjuvant to norepinephrine
• Patients in group I will receive midodrine (10 mg orally every 8 hours) in addition to administered concurrently with ongoing intravenous norepinephrine after being on norepinephrine for more than 24 hrs.
Weaning critically ill patients from norepinephrine without use of midodrine as an adjuvant
Patients in group II with ongoing intravenous norepinephrine only
Locations (1)
Sohag University Hospital
Sohag, Egypt