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Effects of Endogenous GIP on Postprandial Blood Pressure in Healthy Individuals
Sponsor: University Hospital, Gentofte, Copenhagen
Summary
The present study investigates the postprandial role of endogenous glucose-dependent insulinotropic polypeptide (GIP) on cardiovascular haemodynamics, hormone responses, and hypotensive symptoms during a tilt test.
Key Details
Gender
All
Age Range
18 Years - 40 Years
Study Type
INTERVENTIONAL
Enrollment
16
Start Date
2025-05-21
Completion Date
2026-01-31
Last Updated
2025-09-08
Healthy Volunteers
Yes
Conditions
Interventions
GIP(3-30)NH2 / study tool
Selective antagonist of the GIPR, GIP(3-30)NH2
Saline (NaCl 0,9 %) (placebo)
Placebo (NaCl 0,9%)
GIP(1-42)
Agonist of the GIPR, GIP(1-42)
Locations (2)
Center for Clinical Metabolic Research
Copenhagen, Hellerup, Denmark
Center for Clinical Metabolic Research
Copenhagen, Hellerup, Denmark