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NOT YET RECRUITING
NCT06935292
PHASE2/PHASE3

Oral Melatonin VS Nebulized Dexmedetomidine Premedication on Attenuation of Hemodynamic Response to Direct Laryngoscopy and Tracheal Intubation in Hypertensive Patients

Sponsor: Tanta University

View on ClinicalTrials.gov

Summary

The aim of this study is to compare the efficacy of oral melatonin versus nebulized dexmedetomidine in attenuating the hemodynamic response to direct laryngoscopy and endotracheal intubation in controlled hypertensive patients prepared for general anesthesia

Official title: Comparative Study Between Oral Melatonin and Nebulized Dexmedetomidine Premedication on Attenuation of Hemodynamic Response to Direct Laryngoscopy and Tracheal Intubation in Hypertensive Patients: A Prospective Randomized Trial

Key Details

Gender

All

Age Range

40 Years - 60 Years

Study Type

INTERVENTIONAL

Enrollment

70

Start Date

2025-04

Completion Date

2026-04

Last Updated

2025-04-20

Healthy Volunteers

No

Interventions

DRUG

Dexmedetomidine

Nebulized Dexmedetomidine (1μg/kg)

DRUG

Melatonin

Oral Melatonin tablet (5mg)

Locations (1)

Tanta University Hospital

Tanta, El-Gharbia Govenorate, Egypt