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OSNA Versus Ultrastaging to Detect Sentinel Lymph Node Metastasis in Endometrial Cancer
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Summary
Patients enrolled in the study will be randomized before surgery: in one study arm, the search for lymph node metastases in surgically removed sentinel lymph nodes will occur using the ultrastaging method (standard), while in the other arm it will be conducted using the OSNA method.
Official title: One Step Nucleic Acid Amplification (OSNA) Versus Ultrastaging to Detect Sentinel Lymph Node Metastasis in Endometrial Cancer: a Randomized, Multicenter, Controlled Trial (SENT-OSNA Study)
Key Details
Gender
FEMALE
Age Range
Any - Any
Study Type
INTERVENTIONAL
Enrollment
1922
Start Date
2025-07-30
Completion Date
2029-03-17
Last Updated
2025-11-18
Healthy Volunteers
No
Conditions
Interventions
OSNA
The search for lymph node metastases in surgically removed sentinel lymph nodes will occur using the OSNA method
Ultrastaging
The search for lymph node metastases in surgically removed sentinel lymph nodes will occur using the ultrastaging method
Locations (1)
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Rome, Italy, Italy