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Pinaverium Bromide Preventing Post Extracorporeal Shock Wave Lithotripsy Pancreatitis and Painful (PBPEP)
Sponsor: Yanqing Li
Summary
This study aims to evaluate whether perioperative pinaverium bromide (a calcium antagonist) reduces post-ESWL complications (pancreatitis, abdominal pain, infection) in chronic pancreatitis patients with pancreatic duct stones ≥5mm. A single-center, randomized, double-blind, placebo-controlled design will be used, with 288 participants allocated to either pinaverium bromide (100mg tid) or placebo before and after p-ESWL.
Official title: Pinaverium Bromide Preventing Post Extracorporeal Shock Wave Lithotripsy Pancreatitis and Painful (PBPEP): a Single-center, Double-blind, Randomized, Placebo-controlled Trial.
Key Details
Gender
All
Age Range
18 Years - 85 Years
Study Type
INTERVENTIONAL
Enrollment
288
Start Date
2025-03-01
Completion Date
2027-12-30
Last Updated
2025-04-20
Healthy Volunteers
No
Interventions
Pinaverium bromide
Preoperative, intraoperative, and postoperative oral administration of 100mg povidonium bromide in P-ESWL
Placebo for control group
Preoperative, intraoperative, and postoperative oral placebo 100mg for P-ESWL
Locations (1)
Department of Gastroenterology, Qilu hospital of Shandong University
Jinan, Wenhuaxi Road, China