Clinical Research Directory
Browse clinical research sites, groups, and studies.
Randomized Trial of Cold EMR Compared to Hybrid Cold EMR.
Sponsor: The Cleveland Clinic
Summary
The goal of this randomized clinical trial is to learn if a combination of hot and cold EMR technique is associated with a lower risk of polyp recurrence without increasing the risk of complication when removing large polyps. Participants will undergo EMR and return for a follow-up endoscopy in 3-6 months to check for polyp recurrence.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
194
Start Date
2025-05-01
Completion Date
2026-12
Last Updated
2025-11-20
Healthy Volunteers
No
Interventions
Cold EMR
Cold EMR with cold forceps (regular or jumbo forceps) removal of any visible neoplasia that cannot be ensnared.
Hybrid EMR
Cold EMR with hot avulsion of any visible residual neoplasia within the resection bed, in addition to precise APC of the fibrotic bands that may harbor invisible neoplasia within the resection bed.
Locations (2)
Cleveland Clinic Weston
Weston, Florida, United States
Cleveland Clinic
Cleveland, Ohio, United States