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Prospective Observational Study On The Impact Of Nebilet In Blood Pressure Control In Hypertensive Patients (HYIMPACT)
Sponsor: A.Menarini Asia-Pacific Holdings Pte Ltd
Summary
The HYIMPACT study (IMPACT of Nebilet® in Blood Pressure Control in Patients with Hypertension) is a multinational, multicenter, observational, prospective, longitudinal real-world evidence study designed to assess the effectiveness and safety of Nebilet® (nebivolol) in hypertensive patients. The study aims to evaluate changes in systolic and diastolic blood pressure from baseline to 12, 24, and 36 months, as well as treatment adherence, quality of life, prescription patterns, and cardiovascular outcomes. A total of approximately 5,000 hypertensive patients with or without cardiovascular comorbidities will be enrolled across seven Asian countries (Malaysia, Indonesia, the Philippines, Korea, Vietnam, Thailand, and Taiwan). Patients newly initiated on Nebilet®-based treatment or already receiving Nebilet® for no more than two weeks prior to screening will be eligible for inclusion. Patients will be followed at regular intervals for up to three years. The study will also assess the correlation between home and office blood pressure measurements and compare Nebilet® monotherapy with combination therapy in achieving target blood pressure control. The findings from this study will provide real-world insights into the clinical management of hypertension with Nebilet® and its impact on patient outcomes.
Official title: IMPACT of Nebilet in Blood Pressure Control in Patients With HYpertension: An Observational, Longitudinal Study
Key Details
Gender
All
Age Range
18 Years - 100 Years
Study Type
OBSERVATIONAL
Enrollment
4537
Start Date
2023-12-20
Completion Date
2029-03
Last Updated
2025-04-22
Healthy Volunteers
No
Conditions
Locations (49)
Telogorejo Hospital
Semarang, Central Java, Indonesia
Bethesda Hospital
Yogyakarta, Central Java, Indonesia
Panti rapih Hospital
Yogyakarta, Central Java, Indonesia
Husada Utama Hospital
Surabaya, East Java, Indonesia
Premere Surabaya Hospital
Surabaya, East Java, Indonesia
National Cardiovascular Center Harapan Kita Hospital
Jakarta, Jakarta Special Capital Region, Indonesia
Metropolitan Medical Centre Hospital
Jakarta, Jakarta Special Capital Region, Indonesia
Bidakara Medical Centre
Selatan, Jakarta Special Capital Region, Indonesia
PT Ekamas International Hospital
Pekanbaru, Riau, Indonesia
Stella Maris Hospital
Makassar, South Sulawasi, Indonesia
Bukit Asam Medika Hospital
Palembang, South Sumatra, Indonesia
Advent Hospital
Bandung, West Java, Indonesia
Borromeus Hospital
Bandung, West Java, Indonesia
RSUD Syamsudin Hospital
Sukabumi, West Java, Indonesia
Semen Padang Hospital
Padang, West Sumatra, Indonesia
DrThong,Leow,Chiam & Partners
Kuala Lumpur, Kuala Lumpur, Malaysia
Klinik Pembangunan Sdn. Bhd
Kuala Lumpur, Kuala Lumpur, Malaysia
Pantai HKL
Kuala Lumpur, Kuala Lumpur, Malaysia
Columbia Asia Hospital Seremban
Seremban, Negeri Sembilan, Malaysia
Mawar Medical Centre
Seremban, Negeri Sembilan, Malaysia
Bukit Tinggi Medical Centre
Klang, Selangor, Malaysia
Mary Mediatrix Medical Center
Lipa, Batangas, Philippines
Veterans Memorial Medical Center
Quezon City, Manila, Philippines
Kangbuk Samsung Hospital
Seoul, Jongno District Seoul, South Korea
Eunpyeong St. Mary's Hospital
Seoul, Seoul, South Korea
Chonnam National University Hospital
Gwangju, South Korea
Far Eastern Memorial Hospital (FEMH)
New Taipei City, Banqiao, Taiwan
Changhua Christian Hospital (CCH)
Changhua, Changhua County, Taiwan
Chang Gung Memorial Hospital-Chiayi branch (CGMH-CY)
Pozi, Chiayi County, Taiwan
Chung Gung Memorial Hospital-Linkou Branch (CGMH-LK)
Taoyuan District, Guishan District, Taiwan
Hualien Tzu-Chi Hospital (HTCH)
Hualien City, Hualien County, Taiwan
Asia University Hospital (AUH)
Taipei, Nangang Dist., Taiwan
National Cheng Kung University Hospital (NCKUH)
Tainan, North District, Taiwan
Kaohsiung Medical University Hospital (KMUH)
Kaohsiung City, Sanmin District, Taiwan
Taipei Medical University Hospital (TMUH)
Taipei, Xinyi District, Taiwan
Taichung Veterans General Hospital (TVGH)
Taichung, Xitun District, Taiwan
Chi-Mei Medical Center (CMC)
Tainan, Yongkang Dist., Taiwan
MacKay Memorial Hospital (MMH)
Taipei, Zhongshan District, Taiwan
National Taiwan University Hospital (NTUH)
Taipei, Zhongzheng District, Taiwan
Vajira Hospital Namindradhiraj University
Dusit, Bangkok, Thailand
Wetchakarunrasm Hospital
Nong Chok, Bangkok, Thailand
Burapha University
Chon Buri, Changwat Chon Buri, Thailand
Central Chet Institute
Nonthaburi, Changwat Nonthaburi, Thailand
Chiang Mai University
Chiang Mai, Chiang Mai, Thailand
Anand Mahidhol Hospital
Lopburi, Lopaburi, Thailand
CanTho General Hospital
Can Tho, Can Tho City, Vietnam
Hanoi Heart Hospital
Hanoi, Hanoi, Vietnam
Cho Ray Hospital
Ho Chi Minh City, Ho Chi Minh, Vietnam
Hue Central Hospital
Huế, Hue, Vietnam