Clinical Research Directory
Browse clinical research sites, groups, and studies.
Universal Chimeric Antigen Receptor T-Cell (UCAR T-cell) Therapy Targeting CD19/B Cell Maturation Antigen (CD19/BCMA) in Patients With r/r Neurological Autoimmune Diseases
Sponsor: Tianjin Huanhu Hospital
Summary
This is an open label, single-site, dose-escalation study in up to 12 participants with relapsed or refractory Neurological Autoimmune Diseases. This study aims to evaluate the safety and efficacy of the treatment with universal CD19/BCMA CAR T-cells.
Official title: A Clinical Study Evaluating the Safety and Preliminary Efficacy of Universal Allogeneic CAR T-cell Therapy Targeting CD19 and BCMA in Patients With Relapsed / Refractory Neurological Autoimmune Diseases
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
12
Start Date
2025-06-17
Completion Date
2027-10
Last Updated
2025-12-15
Healthy Volunteers
No
Conditions
Interventions
UCAR T-cell
Universal allogeneic anti-CD19/BCMA CAR T-cells
Locations (1)
Tianjin Huanhu Hospital
Tianjin, China