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OPtimal Adult Heart Transplant Immunosuppression With MicroRNA Levels
Sponsor: Inova Health Care Services
Summary
This study aims to develop and refine a microRNA (miR) biomarker panel that can be used to phenotype net immune state after heart transplantation using circulating miRs (associated with drug doses and levels). These miRs will be used to characterize the overall immune state in adult heart transplant patients and predict patients that will go on to develop infection and rejection. MicroRNAs (miRs) are small, non-coding RNA molecules that regulate gene expression and serve as molecular biomarkers found in the circulation.
Key Details
Gender
All
Age Range
18 Years - 99 Years
Study Type
OBSERVATIONAL
Enrollment
250
Start Date
2025-10-28
Completion Date
2032-01-01
Last Updated
2026-03-25
Healthy Volunteers
No
Conditions
Locations (6)
Cedars-Sinai Medical Center
Los Angeles, California, United States
Stanford University
Palo Alto, California, United States
Medical University of South Carolina
Charleston, South Carolina, United States
Vanderbilt University
Nashville, Tennessee, United States
Baylor University Medical Center
Dallas, Texas, United States
Inova Health System
Falls Church, Virginia, United States