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RECRUITING
NCT06939751

OPtimal Adult Heart Transplant Immunosuppression With MicroRNA Levels

Sponsor: Inova Health Care Services

View on ClinicalTrials.gov

Summary

This study aims to develop and refine a microRNA (miR) biomarker panel that can be used to phenotype net immune state after heart transplantation using circulating miRs (associated with drug doses and levels). These miRs will be used to characterize the overall immune state in adult heart transplant patients and predict patients that will go on to develop infection and rejection. MicroRNAs (miRs) are small, non-coding RNA molecules that regulate gene expression and serve as molecular biomarkers found in the circulation.

Key Details

Gender

All

Age Range

18 Years - 99 Years

Study Type

OBSERVATIONAL

Enrollment

250

Start Date

2025-10-28

Completion Date

2032-01-01

Last Updated

2026-03-25

Healthy Volunteers

No

Locations (6)

Cedars-Sinai Medical Center

Los Angeles, California, United States

Stanford University

Palo Alto, California, United States

Medical University of South Carolina

Charleston, South Carolina, United States

Vanderbilt University

Nashville, Tennessee, United States

Baylor University Medical Center

Dallas, Texas, United States

Inova Health System

Falls Church, Virginia, United States