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NOT YET RECRUITING
NCT06942026
PHASE4

Effects of Chlorhexidine Gluconate, Ozonated Water and Hypochlorous Acid Solutions Used in the Oral Care of Patients Supported by Mechanical Ventilation on the Integrity of the Oral Mucosa

Sponsor: Aydin Adnan Menderes University

View on ClinicalTrials.gov

Summary

The purpose of this clinical trial is to learn whether ozonated water and hypochlorous acid solution can restore the integrity of the oral mucosa. In addition, the investigators will learn about the safety of ozonated water and hypochlorous acid solution. The main questions that participants need to answer are: What medical conditions do participants have while taking ozonated water and hypochlorous acid solution? Investigators will compare ozonated water and hypochlorous acid solution with 0.12% chlorhexidine gluconate solution to see if it helps to restore the integrity of the oral mucosa. Participants: Participants will be asked to agree to receive oral care 4 times a day, every day for 1 week.

Key Details

Gender

All

Age Range

18 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

63

Start Date

2025-04-27

Completion Date

2025-09-30

Last Updated

2025-04-24

Healthy Volunteers

Yes

Interventions

DRUG

Control 1

Researchers will perform oral care with ozonated water and hypochlorous acid solution to restore oral mucous membrane integrity.

Locations (1)

Aydın Adnan Menderes Univercity

Aydin, Turkey (Türkiye)