Clinical Research Directory

Inclusion Criteria: * All patients evaluated at Northwestern's IPHP who report bladder function consistent with overactive bladder (urinary urgency, with or without urinary frequency more than 8 times daily or nocturia, with or without urgency urinary incontinence) at their index visit, who are also willing to use a dietary supplement and not initiate additional behavioral, medication or procedural treatment for 12 weeks following pumpkin seed oil extract initiation. Exclusion Criteria: * Patients with any of the following will be excluded from the study: * Use of other supplements that contain pumpkin seed oil * ≥Stage 3 pelvic organ prolapse * Urinary post-void residual ≥150cc * Culture-proven urinary tract infection at time of study enrollment * Recurrent urinary tract infection * Neurogenic bladder * Abdominal or pelvic malignancy * Initiation of new overactive bladder medications or supplements during study period or in the 3 months immediately preceding study enrollment * History of surgery in the past 12 months for pelvic organ prolapse, stress urinary incontinence, urgency urinary incontinence, or fecal or flatal incontinence * Patient's primary language is not English