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ENROLLING BY INVITATION
NCT06944639
NA

Comparative Study of Three Collagen Membranes: 1 Non-cross-linked and 2 Cross-linked

Sponsor: Andrea Ravida

View on ClinicalTrials.gov

Summary

This study is being done to compare how quickly three different types of collagen membranes break down when they are exposed to the mouth. These membranes are often used in dental and oral surgery to help with healing and tissue growth. The goal is to find out if one membrane lasts longer than the others, which may help doctors choose the best option for different procedures. In this study, the membranes will be placed in the mouth in a specific area near the gums of the upper back teeth. The study is designed so that neither the patients nor the researchers evaluating the results will know which membrane is which (this is called a double-blind study). Over time, researchers will measure how much each membrane has broken down. This information may help improve treatment planning and patient outcomes in dental care.

Official title: Comparative Analysis of Three Types of Collagen Membranes Exposed to the Oral Environment: a Randomized Clinical Trial

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

20

Start Date

2025-04-28

Completion Date

2026-07-31

Last Updated

2026-02-17

Healthy Volunteers

Yes

Interventions

DEVICE

Membrane Jason MB GmbH Non-cross-linked (NCL)

The membrane will be stabilized in the oral mucosa using sutures and flowable composite.

DEVICE

Membrane BioMend Extend Glutaraldehyde cross-linked

The membrane will be stabilized in the oral mucosa using sutures and flowable composite.

DEVICE

Membrane OSSIX Agile Ribose cross-linked (RCL)

The membrane will be stabilized in the oral mucosa using sutures and flowable composite.

Locations (1)

University of Pittsburgh, School of Dental Medicine

Pittsburgh, Pennsylvania, United States