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Comparing Pain Relief Between Two Methods of Freezing Injections in Children Having Their Appendix Removed
Sponsor: University of British Columbia
Summary
Laparoscopic appendectomies are the most common emergency surgeries performed in children. Despite being considered minimally invasive surgeries, they can result in substantial postoperative pain and 2 of 3 patients require postoperative opioids. Increased postoperative pain can delay recovery, increase hospital admission time, lead to chronic pain, and cause patient distress. This study aims to reduce postoperative pain in this population by comparing the recovery outcomes associated with the administration of (1) an RSB with coadministration of IV dexamethasone as an LA adjunct (RSB+dex group) prior to the incision with (2) LA infiltration alone by the surgeon (LA group).
Official title: Rectus Sheath Block and Coadministration of Intravenous Dexamethasone for Analgesia After Pediatric Laparoscopic Appendectomy - A Pilot Study
Key Details
Gender
All
Age Range
4 Years - 18 Years
Study Type
INTERVENTIONAL
Enrollment
32
Start Date
2025-05-01
Completion Date
2026-04-27
Last Updated
2025-05-16
Healthy Volunteers
No
Conditions
Interventions
Rectus Sheath Block
Bilateral rectus sheath blocks using an in-plane ultrasound-guided technique with 0.25% bupivacaine with epinephrine 1:200 000 at 0.8 mL/kg (half of total volume per side) up to a maximum of 20 mL prior to the incision.
Local Anesthetic at the Umbilical Port Site
0.25% bupivacaine with epinephrine 1:200 000. Total dose of 0.8 mL/kg (maximum 20 mL) at the umbilical port site.
Intravenous Dexamethasone
Intravenous Dexamethasone delivered concurrent to the RSB. Total dose of 150 mcg/kg up to a maximum of 8 mg.
Local Anesthetic at the Incision Site
The remaining volume of local anesthetic (0.2 mL/kg) can be infiltrated at each of the incision sites at the discretion of the surgeon up to a maximum of 10 mL.
Locations (1)
British Columbia Children's Hospital
Vancouver, British Columbia, Canada