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Treatment of Desmoid Fibromatosis With Arterial Embolization
Sponsor: Istituto Ortopedico Rizzoli
Summary
Desmoid fibromatoses are rare and locally aggressive mesenchymal tumors. The current scientific evidence regarding the efficacy and safety of the treatment of desmoid fibromatosis by arterial embolization is constituted by several retrospective and prospective studies. These studies report promising results through the use of chemoembolization, that is, arterial embolization using particles loaded with chemotherapy. Instead, the type of treatment we propose would consist of injection of embolizing material without the use of chemotherapy, based on the positive results we have consistently reported over the years on arterial embolization of musculoskeletal tumors.
Official title: Treatment of Desmoid Fibromatosis With Arterial Embolization: Retrospective and Prospective Observational Study
Key Details
Gender
All
Age Range
12 Years - Any
Study Type
OBSERVATIONAL
Enrollment
20
Start Date
2025-07-01
Completion Date
2029-02
Last Updated
2025-09-12
Healthy Volunteers
No
Conditions
Interventions
embolization therapy
Identification of the main vessels afferent to the tumor to be treated. -Selective and super-selective catheterization of pathological arterial branches, responsible for the blood supply to the neoplasm, through the use of micro-catheters. - Injection of embolizing material (hydrogel microspheres) - Control of technical success: the embolization will be followed by diagnostic arteriography that will evaluate the success of the procedure (occlusion of more than 90 percent of the pathologic vasculature).
Locations (1)
Istituto Ortopedico Rizzoli
Bologna, BO, Italy