Clinical Research Directory
Browse clinical research sites, groups, and studies.
Pneumatic Leg Compression and Norepinephrine Requirements in Patients Having Non-cardiac Surgery
Sponsor: Universitätsklinikum Hamburg-Eppendorf
Summary
The PLANE trial is a randomized, single-center trial investigating whether pneumatic leg compression reduces the amount of norepinephrine needed to keep MAP above 65mmHg compared to routine care without PLC in patients having non-cardiac surgery under general anesthesia
Official title: Pneumatic Leg Compression and Norepinephrine Requirements in Patients Having Non-cardiac Surgery: a Pilot Monocentric Prospective Randomized Interventional Clinical Trial
Key Details
Gender
All
Age Range
45 Years - Any
Study Type
INTERVENTIONAL
Enrollment
238
Start Date
2025-05-19
Completion Date
2025-10
Last Updated
2025-06-08
Healthy Volunteers
No
Conditions
Interventions
Pneumatic leg compression
Patients assigned to the PLC group will receive a pneumatic leg compression sleeve encompassing the calf and thigh, with sleeve size adjusted according to thigh circumference and manufacturer recommendations. The compression pump will be activated before the start of surgery. After surgery, the responsible trial personnel will deactivate the pump and remove the compression sleeves in the PLC group. There will be no standardized anesthesia management protocol; all decisions regarding hemodynamic management will be made at the discretion of the treating anesthesiologist
Locations (1)
University Medical Center Hamburg-Eppendorf
Hamburg, Hamburg, Germany