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Intrauterine Device Insertion Pain Management
Sponsor: University of Missouri-Columbia
Summary
The goal of this clinical trial is to learn if use of topical benzocaine prior to the injection of lidocaine is effective in decreasing pain experienced during IUD insertion in patients 18 or older. The main question it aims to answer is: Does topical use of benzocaine prior to lidocaine injection during IUD insertion effectively decrease pain experienced? Researchers will compare benzocaine/lidocaine to benzocaine/placebo, placebo/lidocaine, and placebo/placebo to see if use of benzocaine prior to lidocaine injection works more effectively to decrease pain experienced rather than lidocaine, benzocaine, or placebo use alone. Participants will: * Arrive to clinic for previously scheduled IUD insertion * Be screened, approached by research staff, and consented to join the trial * Complete a demographic questionnaire * Be randomly and blindly assigned to one of four groups * Placebo/Placebo * Placebo/Lidocaine * Benzocaine/Placebo * Benzocaine/Lidocaine * All groups will be given 600mg of ibuprofen prior to procedure * Be asked to rate their pain on a visual scale of 1-10 during several distinct points of the procedure. * Be sent an optional survey to their email after the procedure
Official title: Applying a New Method for Pain Control in Intrauterine Device Insertion
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
160
Start Date
2025-06-23
Completion Date
2026-12
Last Updated
2025-07-08
Healthy Volunteers
Yes
Conditions
Interventions
Benzocaine 20%
Benzocaine 20% topical spray
Lidocaine 2%
Lidocaine 2% injectable solution
Sham injection
Sham injection to mimic Lidocaine paracervical block. Will use an injection needle and sham inject (no actual injection of fluid)
Saline 0.9%
Saline spray to mimic use of benzocaine spray
Locations (1)
Missouri OB/GYN Associates-Smiley Lane
Columbia, Missouri, United States