Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

Back to Studies
RECRUITING
NCT06951191
PHASE4

Intrauterine Device Insertion Pain Management

Sponsor: University of Missouri-Columbia

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to learn if use of topical benzocaine prior to the injection of lidocaine is effective in decreasing pain experienced during IUD insertion in patients 18 or older. The main question it aims to answer is: Does topical use of benzocaine prior to lidocaine injection during IUD insertion effectively decrease pain experienced? Researchers will compare benzocaine/lidocaine to benzocaine/placebo, placebo/lidocaine, and placebo/placebo to see if use of benzocaine prior to lidocaine injection works more effectively to decrease pain experienced rather than lidocaine, benzocaine, or placebo use alone. Participants will: * Arrive to clinic for previously scheduled IUD insertion * Be screened, approached by research staff, and consented to join the trial * Complete a demographic questionnaire * Be randomly and blindly assigned to one of four groups * Placebo/Placebo * Placebo/Lidocaine * Benzocaine/Placebo * Benzocaine/Lidocaine * All groups will be given 600mg of ibuprofen prior to procedure * Be asked to rate their pain on a visual scale of 1-10 during several distinct points of the procedure. * Be sent an optional survey to their email after the procedure

Official title: Applying a New Method for Pain Control in Intrauterine Device Insertion

Key Details

Gender

FEMALE

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

160

Start Date

2025-06-23

Completion Date

2026-12

Last Updated

2025-07-08

Healthy Volunteers

Yes

Interventions

DRUG

Benzocaine 20%

Benzocaine 20% topical spray

DRUG

Lidocaine 2%

Lidocaine 2% injectable solution

OTHER

Sham injection

Sham injection to mimic Lidocaine paracervical block. Will use an injection needle and sham inject (no actual injection of fluid)

DRUG

Saline 0.9%

Saline spray to mimic use of benzocaine spray

Locations (1)

Missouri OB/GYN Associates-Smiley Lane

Columbia, Missouri, United States