Clinical Research Directory
Browse clinical research sites, groups, and studies.
The Registry Study of Genetic Alterations of Melanoma in Taiwan
Sponsor: National Health Research Institutes, Taiwan
Summary
Cutaneous melanoma is the most aggressive malignancy in skin cancers. Cutaneous melanoma is a rare disease in Taiwan with an incidence rate of around 1/100,000. Acral lentiginous melanoma is the most common subtype and comprises more than half of cutaneous melanoma in Asia including Taiwan but only 1% in Caucasians. In addition, mucosal melanoma accounts for more than 20% of malignancy melanoma in Taiwan but only 1% in Caucasians. Acral and mucosal melanomas have distinct epidemiological, clinical, pathological and genetic features from non-acral melanoma which is commonly seen in Western countries. Comparing with melanoma in Caucasians, Asian melanoma has higher recurrence rate after primary surgery, lower response rate to immunotherapy, and shorter progression-free survival for immunotherapy and targeted therapy leading generally poor survival outcomes regardless stage.
Official title: T1622 The Registry Study of Genetic Alterations of Melanoma in Taiwan
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
250
Start Date
2022-08-22
Completion Date
2030-12-31
Last Updated
2025-05-06
Healthy Volunteers
Yes
Conditions
Locations (16)
Taipei Veterans General Hospital
Taipei, Taiwan/Taipei, Taiwan
CHANG GUNG MEMORIAL HOSPITAL, Chiayi
Chiayi City, Taiwan
Kaohsiung Chang Gung Memorial Hospital
Kaohsiung City, Taiwan
Kaohsiung Medical University
Kaohsiung City, Taiwan
National Taiwan University Hospital ,NTUH Hsin-Chu Branch
Sindian City, Taiwan
China Medical University Hospital
Taichung, Taiwan
Chung Shan Medical University Hospital
Taichung, Taiwan
Taichung Veterans General Hospital
Taichung, Taiwan
National Cheng Kung University Hospital
Tainan, Taiwan
Koo Foundation Sun Yat-Sen Cancer Center
Taipei, Taiwan
MacKay Memorial Hospital
Taipei, Taiwan
National Taiwan University Hospital
Taipei, Taiwan
Taipei Medical University -Ministry of Health and Welfare Shuang-Ho Hospital
Taipei, Taiwan
Wan Fang Hospital, Taipei Medical University
Taipei, Taiwan
CHANG GUNG MEMORIAL HOSPITAL, Linkou
Taoyuan District, Taiwan
Taoyuan General Hospital, Ministry of Health and Welfare
Taoyuan District, Taiwan