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RECRUITING
NCT06953440
PHASE4

The Effect of Dexamethasone Submucosal Injection After Surgical Extraction of Lower Impacted Third Molars on Trismus and Edema

Sponsor: King Abdulaziz University

View on ClinicalTrials.gov

Summary

This clinical trial aims to investigate whether dexamethasone decreases edema and trismus in adults undergoing lower third molar surgical extraction. The main question it aims to answer is: Does dexamethasone submucosal injection have a positive impact on trismus and edema after third molar surgery compared to conventional postoperative prescription? Participants will: * Be administered with dexamethasone submucosal injection or a placebo after the surgery. * Visit the clinic three times the week after the extraction for follow-up.

Official title: The Effect of Dexamethasone Submucosal Injection After Third Molar Surgery on Trismus and Edema

Key Details

Gender

All

Age Range

18 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

66

Start Date

2024-02-01

Completion Date

2025-06-30

Last Updated

2025-05-01

Healthy Volunteers

No

Interventions

DRUG

Dexamethasone Sodium Phosphate Injection

Patients will receive 4 milligrams of dexamethasone submucosal injection next to the extraction site.

OTHER

Normal Saline (Placebo)

Patients will receive 4 milligrams of normal saline solution next to the extraction site.

Locations (1)

King Abdulaziz University, Faculty of Dentistry

Jeddah, Mecca Region, Saudi Arabia