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RECRUITING
NCT06954675
NA

Comparison of Microbiome Changes in Healthy Adults Following Ketone Ester Consumption

Sponsor: University of California, San Francisco

View on ClinicalTrials.gov

Summary

The goal of this observational study is to learn if a ketone ester can improve the content of the gut microbiome. The main questions it aims to answer are: * Does a ketone ester reduce age-related signatures in the gut microbiome? * What changes occur in the gut microbiome after consuming a ketone ester? Participants will: * Take a ketone ester every day for seven (7) days * Collect and ship stool samples within seven (7) days before, during, and within seven (7) days after the study period * Measure their ketone levels with a urine strip every day after having the drink * Answer questions about their typical diet on a normal day * Record their symptoms, if any arise

Official title: Bacterial Responses to Enteric Alterations After Ketones

Key Details

Gender

All

Age Range

18 Years - 40 Years

Study Type

INTERVENTIONAL

Enrollment

20

Start Date

2025-11-21

Completion Date

2026-09-30

Last Updated

2026-01-26

Healthy Volunteers

Yes

Interventions

DIETARY_SUPPLEMENT

Exogenous ketone ester

25g Bis-octanoyl-(R)-1,3-butanediol (C8)

Locations (1)

UCSF Wayne and Gladys Valley Center for Vision

San Francisco, California, United States