Clinical Research Directory

Inclusion Criteria : * Adults aged 50-74 * Active smoker or weaned smoker for less than 15 years, of at least 20 pack-years * Affiliation with a social security scheme or CMU (beneficiary or beneficiary entitled) * Written informed consent prior to study participation Exclusion Criteria : * History of lung cancer * Thoracic CT scan performed within the previous year * 1-year follow-up not possible * Inability to travel independently to Hôpital Cochin or Hôpital Bichat for scans * People with severe co-morbidities contraindicating exploration and/or management of lung cancers * People in poor general health (=PS2 and above) * People with a history of cancer under active surveillance by thoracic computed tomography (CT and PET scans) * People with rest dyspnea (=mMRC4) * Recent weight loss, altered general condition or hemoptysis, raising suspicion of progressive lung cancer * Signs of respiratory infection (fever, productive cough) * Patients under guardianship, curatorship or protected adults * Inability to give free written informed consent prior to study participation