Clinical Research Directory

Inclusion Criteria: * Patients aged between 18 and 50 years at audiological investigations * Treated for brain tumor, solid cancer, lymphoma or leukemia in childhood, adolescence or at a young adult age (\<25years) * With at least 5 years of cancer-free follow-up after childhood cancer * Patients included in the FCCSS ( https://fccss.fr ) deep cohort of 7670 5-year childhood cancer survivors treated before 2001, or patients who have planned visit in long-term follow-up clinics of Curie Institute and Gustave Roussy, whatever the diagnostic period * Pregnant or breast-feeding women can be included as no risk is identified * With Social security coverage * Signed written informed consent obtained NB: Patients included in another research project are not excluded from this one NB: patients wearing a Lyric hearing prosthesis or any other permanent hearing prosthesis or cochlear implant can be included in the study but will not perform audiological examinations because the audiogram can't be easily performed without hearing prosthesis. Nevertheless, these patients could participate to the study with self-administered questionnaires and could be included as cases (i.e. patients with hearing deficiency) in analyses. Exclusion Criteria: * Patient under guardianship or deprived of his liberty by a judicial or administrative decision or incapable of giving its consent * Patient with unavailable data concerning treatment modalities including cumulative doses of chemotherapy agents or radiation fields and dose