Clinical Research Directory
Browse clinical research sites, groups, and studies.
Adjunctive Effect of Erythritol on Pocket Closure Rates
Sponsor: University of L'Aquila
Summary
This clinical trial is studying whether using erythritol powder during non-surgical periodontal treatment (deep cleaning) helps improve gum health in people with severe periodontitis. Participants with deep gum pockets (4 mm or more) receive standard treatment alone or standard treatment plus cleaning with erythritol powder. The goal is to evaluate if adding erythritol improves outcomes such as healing of gum pockets, bleeding, plaque levels, and gum attachment compared to standard treatment alone.
Official title: Adjunctive Effect of Erythritol on Pocket Closure Rates: RCT
Key Details
Gender
All
Age Range
35 Years - Any
Study Type
INTERVENTIONAL
Enrollment
56
Start Date
2024-11-08
Completion Date
2025-12-31
Last Updated
2025-05-06
Healthy Volunteers
No
Interventions
Non-surgical periodontal therapy + sub-gingival air polishing
Participants receive a single session of non-surgical periodontal therapy (NSPT) using ultrasonic and manual instruments, combined with sub-gingival air polishing using erythritol powder. The treatment is applied to periodontal pockets with probing depth ≥ 4 mm in non-adjacent teeth.
Non-surgical periodontal therapy alone
Participants receive a single session of non-surgical periodontal therapy (NSPT) using ultrasonic and manual instruments.
Locations (1)
University of L'Aquila
L’Aquila, Italy