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Comparison of I-124 PET/CT for the Diagnosis of Thyroid Cancer
Sponsor: Thomas Hope
Summary
Persons diagnosed with thyroid cancer are often treated initially with a thyroidectomy, which is followed by ablation using Iodine-131, a therapy which has been shown to be effective and safe. Imaging of metastatic thyroid cancer has been performed with whole body I-131 and Iodine 123 (I-123) imaging for many decades and use I-123 for staging studies. Iodine 124 (I-124) is a radioisotope of iodine which emits a positron and is imaged using PET (positron emission tomography). This is a single arm prospective trial that evaluates the ability of Iodine-124 (I-124) to detect metastatic thyroid cancer compared to non-interventional, usual care I-123 and I-131 images.
Official title: Comparison of I-124 PET/CT to I-123 Whole Body Imaging for the Diagnosis of Thyroid
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
62
Start Date
2025-07-14
Completion Date
2026-03-31
Last Updated
2026-01-07
Healthy Volunteers
No
Conditions
Interventions
Iodine-124
Given Orally
Positron Emission Tomography (PET)/Computerized tomography (CT)
Combination of PET and CT imaging
Locations (1)
University of California, San Francisco
San Francisco, California, United States