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RECRUITING
NCT06961149
NA

Linked-Color Imaging Versus Indigo Carmine Pump Spraying on the Colorectal Adenoma Detection Rate

Sponsor: Shandong University

View on ClinicalTrials.gov

Summary

Detection and removal of polyps during colonoscopy is crucial for the prevention of colorectal cancer. Indigo carmine spraying up to the colonic mucosa could probably increase the adenoma detection rate, but considering the long withdrawal time of the endoscope and the resulting increase in time and cost. Linked-color imaging (LCI) is a newly developed image-enhanced endoscopy technology. It relies on wave length optimization of three colors (red, green, and blue) to make the lesions appear fuller. LCI improves the visibility of colorectal adenomas and polyps and may increase the detection rate of lesions. In order to explore the clinical application value of Linked-color imaging endoscopy, we performed a prospective, randomized controlled trial to compare adenoma detection rate of Linked-color imaging endoscopy and indigo carmine chromoendoscopy.

Official title: Linked-Color Imaging Versus Indigo Carmine Pump Spraying on the Colorectal Adenoma Detection Rate: a Prospective , Randomized Controlled, Non-inferiority Study

Key Details

Gender

All

Age Range

45 Years - 85 Years

Study Type

INTERVENTIONAL

Enrollment

352

Start Date

2025-04-08

Completion Date

2026-04-01

Last Updated

2025-05-07

Healthy Volunteers

No

Interventions

PROCEDURE

Chromoendoscopy with indigo carmine solution spray

Patients will undergo chromoendoscopy with spraying indigo carmine.

PROCEDURE

Linked-color imaging endoscopy

Patients will undergo Linked-color imaging endoscopy.

Locations (1)

Qilu Hospital of Shandong University

Jinan, Shandong, China