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A Novel Method for Determination of Thromboembolic Stroke Origin
Sponsor: Atlantic Health System
Summary
Rupture of vulnerable carotid, vertebral, and intracranial arterial plaques results in thromboembolic stroke. Identification of these culprit lesions is an important component of post-stroke care. This study seeks to test the feasibility of NaF PET-CT to detect these plaques and alter patient care. Prior studies have shown a high degree of correlation between NaF PET+ lesions and high-risk plaque features on high resolution MRI, including mirocalcification, necrosis, and ulceration.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
20
Start Date
2025-06-01
Completion Date
2026-05-31
Last Updated
2025-05-08
Healthy Volunteers
No
Conditions
Interventions
NaF PET-CT
Following a non-cardiogenic thromboembolic stroke, patients will undergo NaF PET-CT imaging to identify the culprit plaque and any other vulnerable plaques at high risk for rupture
Locations (1)
Overlook Medical Center
Summit, New Jersey, United States