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Post-Operative Biomarker-Guided Precision Medicine For Cardiovascular Risk Reduction
Sponsor: NYU Langone Health
Summary
The goal of this pilot study is to assess enrollment feasibility of a randomized trial of direct oral anticoagulant and high-intensity statin therapy versus usual care in patients with Myocardial Injury after Noncardiac Surgery (MINS). The primary aims of this study are to assess feasibility, study drug adherence, and optimize study design (entry criteria, study endpoints, sample size calculation, site selection) and recruitment strategies for the future multicenter randomized clinical trial studying biomarker-based care in post-operative patients at elevated cardiovascular (CV) risk.
Official title: A Pilot Randomized Trial of Post-Operative Biomarker-Guided Precision Medicine With Rivaroxaban and Atorvastatin for Cardiovascular Risk-Reduction
Key Details
Gender
All
Age Range
45 Years - Any
Study Type
INTERVENTIONAL
Enrollment
50
Start Date
2025-10-07
Completion Date
2027-03-31
Last Updated
2026-04-06
Healthy Volunteers
No
Interventions
Rivaroxaban
Rivaroxaban 2.5mg will be orally administered twice daily for 6 months.
Atorvastatin
Atorvastatin 80mg will be orally administered daily for 6 months.
Locations (1)
NYU Langone Health
New York, New York, United States