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Outcomes Following Limb Sparing Surgery for Soft Tissue Sarcoma
Sponsor: Amsterdam UMC
Summary
The goal of this study is to assess body image, health-related quality of life (QoL), and functioning (gait function, joint function, and walking ability) in patients after resection of localized soft tissue sarcoma (STS) of the extremities. A secondary objective is to assess the influence of different variables (e.g., radiotherapy, ethnicity, etc.) on body image, health-related QoL, and functioning. Patients who underwent a surgical resection at the Amsterdam UMC between 2010 and 2021 will be approached to participate in the study. Participants will complete four questionnaires and undergo a physical examination. Additionally, they will have a 3D gait analysis, a 6-minute walk test with gas analysis, and a muscle strength assessment. Furthermore, muscle volume change will be evaluated on pre- versus postoperative MRI scans.
Official title: Body Image, Health-related Quality of Life, and Function After Soft Tissue Sarcoma Resection
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
150
Start Date
2025-04-24
Completion Date
2028-01-01
Last Updated
2025-12-19
Healthy Volunteers
No
Conditions
Interventions
Surgical resection with or without radiotherapy and/or chemotherapy
The surgical resection of STS serves as the primary treatment, aiming to completely remove the tumor with a wide margin of surrounding healthy tissue to minimize the risk of recurrence. Radiotherapy and/or chemotherapy may be incorporated depending on the tumor's type, stage, and grade.
Locations (1)
Amsterdam UMC
Amsterdam, Netherlands