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Optimizing Perioperative Analgesia to Lower Pain Following Cleft Palate Surgery
Sponsor: Duke University
Summary
The purpose of this study is to compare the use of short acting opioids (fentanyl/hydromorphone) with long acting opioids (methadone) for pain control following cleft palate surgery in infants and young children.
Official title: Perioperative Methadone Use for Cleft Palate Repair: A Randomized Controlled Trial
Key Details
Gender
All
Age Range
6 Months - 4 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2025-06-04
Completion Date
2027-07-04
Last Updated
2025-06-13
Healthy Volunteers
No
Interventions
Methadone hydrochloride
Initial dosing 0.2mg/kg, potential to escalate to 0.25mg/kg following interim analysis
Fentanyl/Hydromorphone
Per routine care
Locations (1)
Duke University Medical Center
Durham, North Carolina, United States