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NOT YET RECRUITING
NCT06962657
PHASE2

Mitigating Toxic Impact: The Role of Coenzyme Q10 in Post-Exposure Protection

Sponsor: University of California, San Diego

View on ClinicalTrials.gov

Summary

This research study is being conducted to see if coenzyme Q10 (a nutritional supplement) might help to prevent and/or alleviate symptoms and health consequences and help to improve quality of life and physical function in residents affected by the February 2023 East Palestine, Ohio train derailment. This is a pilot study that is not powered to achieve benefit but seek to examine effect size and variance to aid in power calculations for a potential future better powered study.

Key Details

Gender

All

Age Range

18 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

20

Start Date

2026-05-15

Completion Date

2028-10-01

Last Updated

2026-05-01

Healthy Volunteers

No

Interventions

DRUG

Ubiquinone 100 mg Oral Soft Gel

Active comparator arm receives three ubiquinone 100mg soft gels per day. Supplement is taken orally in divided doses, with the last soft gel not close to bedtime. Because of the presence of the IND, the dropdown menu does not allow us to choose dietary supplement. The option "drug" was chosen as the closest permissible option.

DRUG

Placebo

Placebo comparator arm receives three placebo soft gels per day. Supplement is taken orally in divided doses, with the last soft gel not close to bedtime. Because of the presence of the IND, the dropdown menu does not allow us to choose dietary supplement. The option "drug" was chosen as the closest permissible option.

Locations (1)

UC San Diego

La Jolla, California, United States