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Mitigating Toxic Impact: The Role of Coenzyme Q10 in Post-Exposure Protection
Sponsor: University of California, San Diego
Summary
This research study is being conducted to see if coenzyme Q10 (a nutritional supplement) might help to prevent and/or alleviate symptoms and health consequences and help to improve quality of life and physical function in residents affected by the February 2023 East Palestine, Ohio train derailment. This is a pilot study that is not powered to achieve benefit but seek to examine effect size and variance to aid in power calculations for a potential future better powered study.
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
20
Start Date
2025-07-01
Completion Date
2028-07-01
Last Updated
2025-05-08
Healthy Volunteers
No
Interventions
Ubiquinone 100 mg Oral Soft Gel
Active comparator arm receives three ubiquinone 100mg soft gels per day. Supplement is taken orally in divided doses, with the last soft gel not close to bedtime.
Placebo
Placebo comparator arm receives three placebo soft gels per day. Supplement is taken orally in divided doses, with the last soft gel not close to bedtime.
Locations (1)
UC San Diego
La Jolla, California, United States