Clinical Research Directory
Browse clinical research sites, groups, and studies.
IL-40 and IL-41 Levels in Sepsis, Septic Shock, and Healthy Individuals
Sponsor: Melahat Yalcin Solak
Summary
This study aims to investigate the blood levels of two recently identified immune-related proteins, Interleukin-40 (IL-40) and Interleukin-41 (IL-41), in patients with sepsis and its more severe form, septic shock. Sepsis is a serious condition caused by an abnormal immune response to infection, which can lead to organ dysfunction. Septic shock represents an advanced stage of sepsis, characterized by significantly higher mortality risk. IL-40 and IL-41 are newly discovered molecules that are thought to play important roles in the immune system. In this study, the blood concentrations of IL-40 and IL-41 in patients diagnosed with sepsis or septic shock will be measured and compared with those in healthy individuals. The findings may contribute to understanding whether these proteins can be used as biomarkers in the diagnosis or monitoring of treatment in sepsis-related conditions.
Official title: Comparison of IL-40 and IL-41 Levels in Patients With Sepsis and Septic Shock to Healthy Individuals
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
80
Start Date
2025-05-15
Completion Date
2025-12-31
Last Updated
2025-05-09
Healthy Volunteers
Yes
Conditions
Interventions
No intervention; Observational study
No interventions are associated with either group. This is an observational study without experimental procedures.
Locations (1)
Harran University Faculty of Medicine, Department of Anesthesiology and Reanimation
Sanliurfa, Turkey (Türkiye)