Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

Back to Studies
RECRUITING
NCT06964061
PHASE1

Evaluate Efficacy, Safety, Tolerability and Biodegradation of PA5346 Ocular Implant in Patients With Open-Angle Glaucoma or Ocular Hypertension

Sponsor: PolyActiva Pty Ltd

View on ClinicalTrials.gov

Summary

The goal of this clinical study is to learn how effective and safe is a single administration of PA5346 Ocular Implant for the reduction of intraocular pressure in adult patients with open-angle glaucoma or ocular hypertension. It will also assess how long it takes for PA5346 Ocular Implant to dissolve in the eye.

Official title: An Open-label Study to Evaluate the Efficacy, Safety, Tolerability, and Biodegradation Period of PA5346 Ocular Implant, 115mcg When Administered to Patients With Open-Angle Glaucoma or Ocular Hypertension

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

12

Start Date

2025-06-10

Completion Date

2026-11-15

Last Updated

2025-12-18

Healthy Volunteers

No

Interventions

COMBINATION_PRODUCT

PA5436 Ocular Implant, 115mcg

The PA5346 Ocular Implant is supplied preloaded into the needle of a single use Administration Device ready for use.

Locations (3)

Cataract & Eye Surgery Centre

Doncaster, Victoria, Australia

Cerulea Pty Ltd

East Melbourne, Victoria, Australia

Melbourne Eye Specialists

Melbourne, Victoria, Australia