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Evaluate Efficacy and Safety of PA5108 Ocular Implants in Primary Open Angle Glaucoma or Ocular Hypertension
Sponsor: PolyActiva Pty Ltd
Summary
The goal of this clinical trial is to determine the dose of PA5108 Ocular Implant that is effective and safe for the reduction of intraocular pressure in adult patients with open-angle glaucoma or ocular hypertension, compared to the standard treatment therapy.
Official title: A Phase 2 Randomized, Multi-center, Parallel, Active-controlled Clinical Study to Evaluate the Safety and Efficacy of Intracameral PA5108 Ocular Implants in Patients With Primary Open-angle Glaucoma, or Ocular Hypertension
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
75
Start Date
2025-05-31
Completion Date
2026-11-15
Last Updated
2025-06-13
Healthy Volunteers
No
Conditions
Interventions
PA5108 Ocular Implant low dose
The PA5108 Ocular Implant low dose is supplied preloaded into the needle of a single use administration device ready for use.
PA5108 Ocular Implant, high dose
The PA5108 Ocular Implant high dose is supplied preloaded into the needle of a single use administration device ready for use.
Latanoprost 0.005% Ophthalmic Solution
Latanoprost eye drops at a concentration of 0.005%
Locations (1)
Eye Research Foundation
Newport Beach, California, United States