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Raman Spectroscopy in the Diagnosis of Extrahepatic Cholangiocarcinoma - a Pilot Study
Sponsor: University Hospital Olomouc
Summary
Diagnosis of extrahepatic cholangiocarcinoma is challenging because the yield of imaging and tissue sampling is limited. Raman spectroscopy is an optical method based on the analysis of scattered monochromatic light. Raman spectroscopy is able to provide a molecular 'fingerprint' of the tissue to determine its type. The aim of this pilot study was to develop a methodology for in vivo Raman spectroscopy in bile ducts to improve the current diagnostic capabilities of extrahepatic cholangiocarcinoma.
Official title: Raman Spectroscopy in the Diagnosis of Extrahepatic Cholangiocarcinoma
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
20
Start Date
2023-02-04
Completion Date
2025-07-30
Last Updated
2025-07-02
Healthy Volunteers
No
Conditions
Interventions
Endoscopic retrograde cholangiopancreatography (ERCP)
Insertion of a endoscopic fiber-optic Raman probe under fluoroscopic control during endoscopic retrograde cholangiopancreatography to measure Raman spectra of extrahepatic cholangiocarcinoma and healthy bile duct.
Locations (1)
Peter Slodička
Olomouc, Olomoucký kraj, Czechia