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Study of DCC-2812 in Participants With Advanced Genitourinary Cancers
Sponsor: Deciphera Pharmaceuticals, LLC
Summary
This is a multicenter clinical trial to evaluate the safety and preliminary activity of the selective general control nonderepressible 2 (GCN2) activator DCC-2812 as monotherapy in advanced/metastatic renal cell carcinoma (RCC), urothelial carcinoma, and castration-resistant prostate cancer.
Official title: An Open-label, Phase 1 Study of DCC-2812 Monotherapy in Participants With Advanced or Metastatic Renal Cell Carcinoma, Urothelial Cancer, or Castration-Resistant Prostate Cancer
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2025-08-27
Completion Date
2029-02
Last Updated
2026-02-11
Healthy Volunteers
No
Interventions
DCC-2812
Administered orally
Locations (3)
Dana-Farber Cancer Institute
Boston, Massachusetts, United States
NEXT Oncology, Austin
Austin, Texas, United States
NEXT Oncology, San Antonio
San Antonio, Texas, United States