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RECRUITING
NCT06966024
PHASE1

Study of DCC-2812 in Participants With Advanced Genitourinary Cancers

Sponsor: Deciphera Pharmaceuticals, LLC

View on ClinicalTrials.gov

Summary

This is a multicenter clinical trial to evaluate the safety and preliminary activity of the selective general control nonderepressible 2 (GCN2) activator DCC-2812 as monotherapy in advanced/metastatic renal cell carcinoma (RCC), urothelial carcinoma, and castration-resistant prostate cancer.

Official title: An Open-label, Phase 1 Study of DCC-2812 Monotherapy in Participants With Advanced or Metastatic Renal Cell Carcinoma, Urothelial Cancer, or Castration-Resistant Prostate Cancer

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

60

Start Date

2025-08-27

Completion Date

2029-02

Last Updated

2026-02-11

Healthy Volunteers

No

Interventions

DRUG

DCC-2812

Administered orally

Locations (3)

Dana-Farber Cancer Institute

Boston, Massachusetts, United States

NEXT Oncology, Austin

Austin, Texas, United States

NEXT Oncology, San Antonio

San Antonio, Texas, United States